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Cover of BioTechniques
March 1999


Harequin-FISH staining of metaphase preparations of the human B-lymphoblastoid cell line, TK6. A second-division metaphase cell shows staining of chromosome 2 (red). A sister chromatid exchange on the long arm of one of the chromosomes is also visible.

Image from

Jordan, R., Edington, J., Evans, H.H. and J.L. Schwartz, Detection of Chromosome Aberrations by FISH as a Function of Cell Division Cycle (Harlequin-FISH), BioTechniques 26:532-534 (March 1999).

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